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One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein-DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create unified view of the field and a fuller understanding of protein-DNA interactions.
- Sales Rank: #547000 in Books
- Brand: Brand: Cold Spring Harbor Laboratory Press
- Published on: 2013-02-28
- Original language: English
- Number of items: 1
- Dimensions: 6.60" h x .40" w x 9.00" l, .85 pounds
- Binding: Paperback
- 208 pages
- Used Book in Good Condition
Most helpful customer reviews
2 of 2 people found the following review helpful.
Comprehensive Review of TF-DNA
By Wenqiang
I'm a student in bioinformatics program doing research in TF-DNA interaction.
This book provides three different views: structure, physics, and bioinformatics. The book is easy to follow, and the author is very famous in this field.
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